…And ridding yourself of guilt. How can you do this? Any techniques?
Discuss… 
Meditation, as that changes your brain patterns permanently.
May I ask why you want to desensitize your conscience? just to know if meditation is the best solution for your requirement, you understand… 
How are you doing, Lumi? well, I hope…?
Did you kill another person?
Perhaps we crave a little homicide ourselves, RU?
Well, I don’t want to incriminate myself here anymore than I already have…
Watch Batman The Dark Knight except skip the end… that should do it…
Get out into the world and stop depending on others. It’s easy to do what you have to do, when you really have to.
I think if you keep consistency in defaming yourself, others tend to pull you up deliberately so if you say that i am guilty a thousand times, others around will apologize for it on ur behalf and boost your senses.
Its a tested formula.
You could define conscience as moral anxiety, and use systematic desensitization. There are three steps in the self-administered systematic desensitization procedure which you could use:
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Relaxation;
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Constructing an moral anxiety hierarchy;
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Pairing relaxation with the situations described in your moral anxiety hierarchy.
Watch pulp fiction, reservoir dogs, requiem for a dream, pi, saving private ryan, fight club, to name just a few while stoned. Get real high and drunk alot until you can no longer think process takes about a year… then detox and sober up… Don’t lose you sanity.
All you need to know:
I might try that.
I just think that my life would run more smoothly, if I was able to leave the last remnants of my cultural programing behind, and look only to myself for validation on subjects that are taboo and would (to others especially) normally involve embarrassment, anxiety and guilt etc…
Sound and practical 
Why would you want to remove guilt? its a very usefull emmotion that helps us to function in a human society. Are you planning on becoming a hermit?
Try meditation.
Mindlessness get’s rid of all self-regulating mechanisms.
it’s a perfect way to avoid suffering - the other regulating sensation.
I disagree completely with this and anyone else who said it such as Magsj.
Many forms of psychotherapy help you blame others for your problems thus ridding yourself of a sense of responsibility.
Meditation is about facing up to the truth of your experience.
By clearing your mind of any thought concerning it and just feeling it. How easy to feel empty when consciousness is stream of thought.
What?