Nietzsche's "Horizons"

I’m interested in the concept of “Horizons” Nietzsche presents in The Use and Abuse of History. They are, as I understand them, mental construction of “truths” used by an individual to remain sane and productive in life.

How do these horizons relate to ethics? Am I right or fully wrong in saying that using the horizons concept as a basis, Nietzsche would reject any ethical system that attempts to adopt itself uniformly to all humanity? How much room is there for synergy?