Every good pick up line deserves a good push back.
Pick up line about chemistry?
Definitely reversible.
Some say you never really touch anyone because there is space between everything.
The come back: Is that why no one ever felt you penetrate?
#notplaying
If the above still begets a third attempt, which will invariably involve self-depreciation (the pity move)…
…the response shall be something like:
You’re not a piece of shit. You’re just full of shit you anally retain.